US Patent Issued to GlaxoSmithKline Intellectual Property (No. 4), IDEAYA Biosciences on Aug. 26 for "Thiadiazolyl derivatives as DNA polymerase theta inhibitors and uses thereof" (Pennsylvania, California, Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,131, issued on Aug. 26, was assigned to GlaxoSmithKline Intellectual Property (No. 4) Ltd. (Stevenage, Great Britain) and IDEAYA Biosciences Inc. (South San Francisco, Calif.).

"Thiadiazolyl derivatives as DNA polymerase theta inhibitors and uses thereof" was invented by Janos Botyanszki (Norristown, Pa.), Kevin Duffy (Phoenixville, Pa.), Young Eun Choi (Cambridge, Mass.), Claire L. Neilan (South San Francisco, Calif.) and Marcus M. Fischer (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compounds of Formula (I):that inhibit DNA Polymerase Theta (PolTheta) activity, in particular inhibit PolTheta acti...