ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,946, issued on Aug. 19, was assigned to Geron Corp. (Foster City, Calif.).
"Use of a Janus kinase inhibitor and a telomerase inhibitor for the treatment of myeloproliferative neoplasms" was invented by Xiaoli Wang (New York) and Fei Huang (Foster City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure include methods for treating a myeloproliferative neoplasm. Methods according to certain embodiments include co-administering to a subject a Janus kinase (JAK) inhibitor and a telomerase inhibitor comprising an oligonucleotide and a lipid moiety linked to the 5' and/or 3' end of the oligonucleotide. Methods for inducing ap...