ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,864, issued on Nov. 11, was assigned to GENETHON (Evry-Courcouronnes, France), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (Paris) and UNIVERSITE D'EVRY-VAL-D'ESSONNE (Evry-Courcouronnes, France).

"Production of large-sized quasidystrophins using overlapping AAV vectors" was invented by Isabelle Richard (Corbeil Essonnes, France) and William Lostal (Savigny sur Orge, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention concerns a quasidystrophin (QD) having the structure CH1CH2H1R1R2R3H2R8R9 in its N-terminal part and advantageously further comprising the R16 and R17 rod domains, as well as the dual AAV ...