US Patent Issued to Generation Bio on June 24 for "Non-viral DNA vectors and uses thereof for expressing FVIII therapeutics" (Massachusetts Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,275, issued on June 24, was assigned to Generation Bio Co. (Cambridge, Mass.).

"Non-viral DNA vectors and uses thereof for expressing FVIII therapeutics" was invented by Douglas Anthony Kerr (Cambridge, Mass.), Debra Klatte (Cambridge, Mass.), Phillip Samayoa (Cambridge, Mass.) and Nathaniel Silver (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application describes ceDNA vectors having linear and continuous structure for delivery and expression of a transgene. ceDNA vectors comprise an expression cassette flanked by two ITR sequences, where the expression cassette encodes a transgene encoding FVIII protein. Some ceDNA vectors ...