ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,906, issued on July 22, was assigned to Fred Hutchinson Cancer Center (Seattle).
"Immunomodulatory fusion proteins and uses thereof" was invented by Shannon K. Oda (Lake Forest Park, Wash.), Philip D. Greenberg (Mercer Island, Wash.) and Thomas M. Schmitt (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a T cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion p...