US Patent Issued to Foresee Pharmaceuticals USA on Dec. 23 for "Matrix metalloproteinase (MMP) inhibitors and methods of use thereof" (American, Taiwanese Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,460, issued on Dec. 23, was assigned to Foresee Pharmaceuticals USA Inc. (Newark, Del.).

"Matrix metalloproteinase (MMP) inhibitors and methods of use thereof" was invented by Wenjin Yang (Foster City, Calif.) and Kai-Wei Chang (Taichung, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Hydantoin based compounds of formula (I) useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmonary disease (COPD), emphysema, acu...