ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,584, issued on May 27, was assigned to EXOSOME THERAPEUTICS INC. (San Diego).

"cGMP exosome loaded therapeutics for treating sickle cell disease" was invented by Gerardo Rodriguez-Araujo (Rancho Santa Fe, Calif.), Stephen R. Puckett Sr. (Indian Land, S.C.), Stephen R. Puckett Jr. (Gainesville, Fla.) and Mitchell W. Puckett (Matthews, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A composition for treating sickle cell disease includes a cGMP exosome having a size range between 60 nm to 120 nm, which may be extracted from a human mesenchymal stem cell (hMSC) or human PBMC at 320,000 g, wherein the cGMP exosome may be loaded with a Hemoglobin Sub...