US Patent Issued to Epizyme, Eisai R&D Management on March 18 for "Salt form of a human histone methyltransferase EZH2 inhibitor" (Massachusetts, New Hampshire Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,386, issued on March 18, was assigned to Epizyme Inc. (Cambridge, Mass.) and Eisai R&D Management Co. Ltd. (Tokyo).

"Salt form of a human histone methyltransferase EZH2 inhibitor" was invented by Kevin Wayne Kuntz (Woburn, Mass.), Kuan-Chun Huang (Andover, Mass.), Hyeong Wook Choi (Andover, Mass.), Kristen Sanders (Gilmanton, N.H.), Steven Mathieu (Andover, Mass.), Arani Chanda (Malden, Mass.) and Francis Fang (Andover, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide hy...