US Patent Issued to EmendoBio on Oct. 7 for "Differential knockout of an allele of a heterozygous ELANE gene-II" (Israeli Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,334, issued on Oct. 7, was assigned to EmendoBio Inc. (Wilmington, Del.).

"Differential knockout of an allele of a heterozygous ELANE gene-II" was invented by David Baram (Tel Aviv, Israel), Lior Izhar (Tel Aviv, Israel), Asael Herman (Ness-Ziona, Israel), Rafi Emmanuel (Ramla, Israel), Michal Golan Mashiach (Ness-Ziona, Israel) and Joseph Georgeson (Rehovot, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for inactivating in a cell a mutant allele of the elastase, neutrophil expressed gene (ELANE gene) gene having a mutation associated with severe congenital neutropenia (SCN) or cyclic neutropenia (CyN) and which cell is heterozygous a...