US Patent Issued to EMENDOBIO on Oct. 28 for "Differential knockout of an allele of a heterozygous apolipoprotein A1 (APO1A) gene" (Israeli Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,705, issued on Oct. 28, was assigned to EMENDOBIO INC. (Wilmington, Del.).

"Differential knockout of an allele of a heterozygous apolipoprotein A1 (APO1A) gene" was invented by David Baram (Tel Aviv, Israel), Lior Izhar (Tel Aviv, Israel), Asael Herman (Ness Ziona, Israel), Rafi Emmanuel (Ramla, Israel), Michal Golan Mashiach (Ness Ziona, Israel) and Joseph Georgeson (Rehovot, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "RNA molecules comprising a guide sequence portion having 17-20 nucleotides in the sequence of 17-20 contiguous nucleotides set forth in any one of SEQ ID NOs: 1-1313 and compositions, methods, and uses thereof."

The patent...