US Patent Issued to Eli Lilly and Co. on March 4 for "Adeno-associated virus (AAV) systems for treatment of genetic hearing loss" (Massachusetts, Florida Inventors)

ALEXANDRIA, Va., March 5 -- United States Patent no. 12,241,077, issued on March 4, was assigned to Eli Lilly and Co. (Indianapolis).

"Adeno-associated virus (AAV) systems for treatment of genetic hearing loss" was invented by Christopher Bartolome (Billerica, Mass.), Luis David Jaramillo (Cambridge, Mass.), Adrian M. Timmers (Burlington, Mass.), Steven Pennock (Leominster, Mass.) and Mark Shearman (Alachua, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are codon optimized nucleic acid sequences encoding gap junction protein beta 2 (GJB2), and associated genetic elements, for use in recombinant adeno-associated virus (rAAV)-based gene therapy. The rAAV vectors through which GJB2 is pac...