US Patent Issued to East Carolina University on Aug. 12 for "Methods and compositions for maintaining opioid efficacy in the treatment of pain" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,551, issued on Aug. 12, was assigned to East Carolina University (Greenville, N.C.).

"Methods and compositions for maintaining opioid efficacy in the treatment of pain" was invented by Kori Brewer (Greenville, N.C.) and Stefan Clemens (Greenville, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for treating and/or managing pain. The invention further provides methods for reducing or inhibiting opioid tolerance, reducing risk of opioid addiction or dependence, restoring opioid efficacy, and enhancing the therapeutic effect of an opioid. The invention further provides compositions for use in the methods of th...