ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,414,924, issued on Sept. 16, was assigned to Duke University (Durham, N.C.).
"Lasofoxifene treatment of breast cancer" was invented by Kaitlyn Andreano (Durham, N.C.), Ching-yi Chang (Durham, N.C.), Donald P. McDonnell (Chapel Hill, N.C.) and Stephanie L. Gaillard (Durham, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides methods for treating estrogen receptor positive (ER+) cancer in women with an effective amount of lasofoxifene, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The disclosure also includes the detection of the Estrogen Receptor 1 (ESR1) gene mutations that lead to endocrine resistance and tr...