US Patent Issued to DANA-FARBER CANCER INSTITUTE on Sept. 30 for "Protein tag to induce ligand dependent degradation of protein/protein-fusions" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,459, issued on Sept. 30, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Protein tag to induce ligand dependent degradation of protein/protein-fusions" was invented by Eric S. Fischer (Chestnut Hill, Mass.), Shourya Sonkar Roy Burman (Brookline, Mass.), Tyler Faust (Brookline, Mass.), Hojong Yoon (Cambridge, Mass.) and Radoslaw P. Nowak (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compositions and methods for modulating protein abundance in a target-specific manner via degron tags."

The patent was filed on Sept. 17, 2020, under Application No. 17/642,874.

*For further information, including images, char...