ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,452, issued on June 3, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).
"Degraders of WEE1 kinase" was invented by Nathanael S. Gray (Boston), David Scott (Newton, Mass.), Zhengnian Li (Brookline, Mass.), Benika J. Pinch (Brookline, Mass.), Calla Olson (Brookline, Mass.), Eric S. Fischer (Chestnut Hill, Mass.), Radoslaw P. Nowak (Boston) and Katherine A. Donovan (Brookline, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are bifunctional compounds (degraders) that target Wee1 tyrosine kinase for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat di...