ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,960, issued on July 15, was assigned to Dana-Farber Cancer Institute Inc. (Boston).
"Selective targeting of ubiquitin- and ubiquitin-like E1-activating enzymes by structurally-stabilized peptides" was invented by Loren D. Walensky (Newton, Mass.), Ann Morgan Cathcart (Cambridge, Mass.) and Gregory H. Bird (Pelham, N.H.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure features structurally-stabilized and/or warhead-bearing structurally stabilized peptide inhibitors for targeting ubiquitin activating enzymes (E1). Also disclosed are methods of using such structurally-stabilized and warhead-bearing structurally stabilized peptides in the ...