US Patent Issued to DANA-FARBER CANCER INSTITUTE on Dec. 9 for "Degraders of cyclin-dependent kinase 7 (CDK7) and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,251, issued on Dec. 9, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Degraders of cyclin-dependent kinase 7 (CDK7) and uses thereof" was invented by Nathanael S. Gray (Boston), Guangyan Du (Jamaica Plain, Mass.), Tinghu Zhang (Brookline, Mass.), Zhixiang He (Brookline, Mass.), Nicholas Kwiatkowski (Brookline, Mass.) and Jie Jiang (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are bispecific compounds (degraders) that target CDK7 for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat disease."

The patent was filed on Aug. 4, 2020, ...