US Patent Issued to Dana-Farber Cancer Institute on Aug. 5 for "Allosteric EGFR inhibitors and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,080, issued on Aug. 5, was assigned to Dana-Farber Cancer Institute Inc. (Boston).

"Allosteric EGFR inhibitors and methods of use thereof" was invented by Courtney A. Cullis (Bedford, Mass.), Krista E. Gipson (Medford, Mass.), Yongbo Hu (Winchester, Mass.), Shih-Chung Huang (Lexington, Mass.), Nathanael S. Gray (Jamaica Plain, Mass.), David A. Scott (Newton, Mass.), Thomas Gero (Stow, Mass.), David Heppner (Brookline, Mass.), Tyler Beyett (Brookline, Mass.), Ciric To (Medford, Mass.) and Michael Eck (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to a compound of Formula (I), which acts as an allosteric inhibit...