US Patent Issued to DAIICHI SANKYO on Feb. 11 for "Treatment of metastatic brain tumor by administration of an antibody-drug conjugate" (Japanese Inventors)

ALEXANDRIA, Va., Feb. 12 -- United States Patent no. 12,220,604, issued on Feb. 11, was assigned to DAIICHI SANKYO COMPANY Ltd. (Tokyo).

"Treatment of metastatic brain tumor by administration of an antibody-drug conjugate" was invented by Kiyoshi Sugihara (Tokyo) and Chiaki Ishii (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A therapeutic agent for a metastatic brain tumor comprising, as an active component, an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents a connecting position to an antibody) is conjugated to the antibody via a thioether bond and/or a method of treatment for a metastatic brain tumor, comprising administering the antibody-dr...