US Patent Issued to DAIICHI SANKYO on Dec. 16 for "Combination of antibody-drug conjugate and tubulin inhibitor" (Japanese Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,465, issued on Dec. 16, was assigned to DAIICHI SANKYO COMPANY Ltd. (Tokyo).

"Combination of antibody-drug conjugate and tubulin inhibitor" was invented by Yusuke Ogitani (Tokyo), Chiaki Ishii (Tokyo), Yasuki Kamai (Tokyo), Kiyoshi Sugihara (Tokyo) and Shotaro Nagase (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical composition, wherein an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents a connecting position to an antibody) is conjugated to the antibody via a thioether bond, and a tubulin inhibitor are administered in combination, and a method of treatment, wherein the an...