US Patent Issued to CYTOMX THERAPEUTICS on Nov. 4 for "Matrix metalloprotease-cleavable and serine protease-cleavable substrates and methods of use thereof" (California, Oregon Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,999, issued on Nov. 4, was assigned to CYTOMX THERAPEUTICS INC. (South San Francisco, Calif.).

"Matrix metalloprotease-cleavable and serine protease-cleavable substrates and methods of use thereof" was invented by Stephen James Moore (Danville, Calif.), Margaret Thy Luu Nguyen (San Francisco), Daniel Robert Hostetter (Palo Alto, Calif.), Olga Vasiljeva (Cupertino, Calif.), Jason Gary Sagert (San Mateo, Calif.), Jonathan Alexander Terrett (Cupertino, Calif.) and James William West (Bend, Ore.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates generally to polypeptides that include at least a first cleavable moiety (CM1) that is a sub...