ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,522, issued on Feb. 18, was assigned to COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colo.) and CETYA THERAPEUTICS INC. (Fort Collins, Colo.).

"Synthesis of structural analogs of largazole and associated compounds" was invented by Robert M. Williams (Ft. Collins, Colo.), Sivanagireddy Koti (Ft. Collins, Colo.), Subhadip De (Ft. Collins, Colo.), Anil M. Shelke (Ft. Collins, Colo.), Ryan E. Cerbone (Ft. Collins, Colo.) and Nobuyoshi Yasuda (Ft. Collins, Colo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are various synthetic methods to prepare structural analogs of largazole and derivatives thereof. One structural analog is...