US Patent Issued to City of Hope on Nov. 25 for "Use of triplex CMV vaccine in CAR T cell therapy" (California Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,672, issued on Nov. 25, was assigned to City of Hope (Duarte, Calif.).

"Use of triplex CMV vaccine in CAR T cell therapy" was invented by Don J. Diamond (Duarte, Calif.), Xiuli Wang (Temple City, Calif.) and Stephen J. Forman (Duarte, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for treating a patient comprising: (a) providing a composition comprising a population of T cells expressing both a chimeric antigen receptor (CAR) and a T cell receptor specific for a cytomegalovirus (CMV) antigen; (b) administering the composition to the patient; and (c) administering to the patient a viral vector encoding: (i) CMV pp65 and (ii) a fusion ...