US Patent Issued to CITY OF HOPE on Nov. 18 for "Modification of small RNAs for therapeutic uses" (California Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,548, issued on Nov. 18, was assigned to CITY OF HOPE (Duarte, Calif.).

"Modification of small RNAs for therapeutic uses" was invented by John J. Rossi (Duarte, Calif.) and Minsun Song (Duarte, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for improving stability of small therapeutic RNAs by adding one or more non-templated nucleotides such as cytidines and uridines to the 3' end of the small therapeutic RNAs. Also disclosed are modified small therapeutic RNAs comprising one or more non-templated nucleotides such as cytidines and uridines at the 3' end and pharmaceutical compositions comprising such modified small therape...