US Patent Issued to CITY OF HOPE on June 24 for "Genetically stable recombinant modified vaccinia Ankara (RMVA) vaccines and methods of preparation thereof" (California, South Carolina Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,337,032, issued on June 24, was assigned to CITY OF HOPE (Duarte, Calif.).

"Genetically stable recombinant modified vaccinia Ankara (RMVA) vaccines and methods of preparation thereof" was invented by Don J. Diamond (Glendora, Calif.) and Zhongde Wang (Mount Pleasant, S.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A vaccine comprising an immunologically effective amount of recombinant modified vaccinia Ankara (rMVA) virus which is genetically stable after serial passage and produced by a) constructing a transfer plasmid vector comprising a modified H5 (mH5) promoter operably linked to a DNA sequence encoding a heterologous foreign protein antigen, w...