US Patent Issued to CITY OF HOPE on Jan. 13 for "Cell penetrating conjugates and methods of use thereof" (California Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,445, issued on Jan. 13, was assigned to CITY OF HOPE (Duarte, Calif.).

"Cell penetrating conjugates and methods of use thereof" was invented by Andreas Herrmann (La Jolla, Calif.), Hua Yu (Glendora, Calif.), Piotr Marek Swiderski (San Dimas, Calif.), John Ernest Shively (Arcadia, Calif.) and Lin Li (Monrovia, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular deliv...