ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,374, issued on Dec. 16, was assigned to CHIROGATE INTERNATIONAL INC. (Yangmei, Taiwan).

"Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom" was invented by Chun-Yu Lin (Yangmei, Taiwan), Tzyh-Mann Wei (Yangmei, Taiwan) and Shih-Yi Wei (Yangmei, Taiwan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A racemic or optically enriched compound of Formula 1:wherein P is H or a protective group for hydroxyl groups; and X is Cl, Br, I, or -CH2CH2CH2COOR1, wherein R1 is C1-7-alkyl or C7-11-aralkyl."

The patent was filed on Sept. 14, 2023, under Application No. 18/467,441.

*For ...