US Patent Issued to Children's Medical Center, Dana-Farber Cancer Institute on April 8 for "Use of toll-like receptor 2 (TLR-2) agonist for modulating human immune response" (Massachusetts, California Inventors)

ALEXANDRIA, Va., April 9 -- United States Patent no. 12,268,739, issued on April 8, was assigned to Children's Medical Center Corp. (Boston) and Dana-Farber Cancer Institute Inc. (Boston).

"Use of toll-like receptor 2 (TLR-2) agonist for modulating human immune response" was invented by David J. Dowling (Brighton, Mass.), Ofer Levy (Cambridge, Mass.), Francesco Borriello (Jamaica Plain, Mass.), David A. Scott (Newton, Mass.) and Spencer E. Brightman (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are Toll-like receptor 2 (TLR2) agonists for use in enhancing human immune response and/or as adjuvants in vaccines. The TLR2 agonists include thiophenes, imidazoles, or phenyl-containing c...