US Patent Issued to Children's Hospital Medical Center on Dec. 16 for "Methods of generating and expanding hematopoietic stem cells" (Ohio Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,597, issued on Dec. 16, was assigned to Children's Hospital Medical Center (Cincinnati).

"Methods of generating and expanding hematopoietic stem cells" was invented by Takanori Takebe (Cincinatti, Ohio) and Kyle Lewis (Cincinatti, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Production and maintenance of hematopoietic stem cells in in vitro culture systems has proven to be elusive. Disclosed herein are hematopoietic stem cell compositions that originate from organoids such as liver organoids. These organoids also comprise a rare type of immune cell that is not yet fully elucidated due to the difficulty in isolating said immune cell from biolo...