US Patent Issued to Children's Hospital Medical Center on April 8 for "Compositions and methods for treating cancer" (Ohio, Maryland Inventors)

ALEXANDRIA, Va., April 9 -- United States Patent no. 12,268,680, issued on April 8, was assigned to Children's Hospital Medical Center (Cincinnati).

"Compositions and methods for treating cancer" was invented by Nicolas Nassar (Cincinnati), William Seibel (Liberty Township, Ohio), Anjelika Gasilina (Bethesda, Md.) and Jose Cancelas (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "A small molecule compound IODVA1 has been found to have cellular inhibitory activity against several transformed cell lines including Ras-driven cells. IODVA1 decreases cell-cell and cell-extra cellular matrix interactions and reduces growth of Ras-driven tumors. Applicants also synthesized compound NIRA2 and showed in vit...