ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,826, issued on Nov. 25, was assigned to CHIESI FARMACEUTICI S.P.A. (Parma, Italy).

"Pyridazinyl amino derivatives as ALK5 inhibitors" was invented by Daniela Pizzirani (Parma, Italy), Matteo Biagetti (Parma, Italy), Paolo Ronchi (Parma, Italy), Paolo Bruno (Parma, Italy), Sara Guariento (Parma, Italy), Barbara Bertani (Parma, Italy), Daniele Pala (Parma, Italy) and Alessio Barilli (Parma, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound of general formula (I) inhibiting the transforming growth factor-Beta (TGF-Beta) type I receptor (ALK5), methods of preparing such compounds, pharmaceutical composition...