US Patent Issued to CHARITE-UNIVERSITATSMEDIZIN BERLIN on July 22 for "Specific t cell receptors against epitopes of mutant MYD88L265P protein for adoptive T cell therapy" (American, German Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,717, issued on July 22, was assigned to CHARITE-UNIVERSITATSMEDIZIN BERLIN (Berlin).

"Specific t cell receptors against epitopes of mutant MYD88L265P protein for adoptive T cell therapy" was invented by Antonio Pezzutto (Berlin) and Ozcan Cinar (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are adoptive T cell therapies or T cell receptor (TCR) gene therapies from the treatment of cancer. The therapies utilize a nucleic acid encoding at least one TCR alpha or beta chain construct of a TCR construct capable of specifically binding to a MYD88 L265P peptide of SEQ ID NO: 2 in the context of HLA-B*07:02 having a high a...