ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,359, issued on April 22, was assigned to Cedars-Sinai Medical Center (Los Angeles).
"Variants of TNFSF15 and DCR3 associated with Crohn's disease" was invented by Dermot P. McGovern (Los Angeles).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods and compositions related to the discovery of associations in TNFSF15 15 and DcR3 genetic loci across in Caucasian, Puerto Rican, and Korean Crohn's Disease, as demonstrated via trans-ethnic fine mapping. The present invention provides methods of quantifying risk and diagnosing susceptibility to Crohn's disease in a subject by determining the presence of one or more risk variants are a...