US Patent Issued to CASE WESTERN RESERVE UNIVERSITY on Nov. 25 for "Autologous and allogenic HIV-1 proteins for the treatment of latent HIV-1 infection" (Canadian Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,666, issued on Nov. 25, was assigned to CASE WESTERN RESERVE UNIVERSITY (Cleveland).

"Autologous and allogenic HIV-1 proteins for the treatment of latent HIV-1 infection" was invented by Eric J. Arts (Ontario, Canada) and Jamie Mann (Ontario, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of reducing a latent HIV-specific memory-CD4+ T cell pool in a subject includes administering to the subject at least one HIV-1 protein and a pharmaceutically acceptable carrier, wherein the at least one HIV-1 protein is derived from an allogenic infecting HIV-1 virus, and wherein the HIV-1 protein stimulates latent HIV-specific memory CD4+ T cells ...