ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,748, issued on Jan. 27, was assigned to California Institute of Technology (Pasadena, Calif.).

"Engineered beta-subunit of tryptophan synthase for production of non-canonical amino acids" was invented by Andrew Richard Buller (Pasadena, Calif.), Sabine Brinkmann-Chen (Alhambra, Calif.), Michael Herger (Pasadena, Calif.), David K. Romney (Pasadena, Calif.), Javier Murciano Calles (Ubeda Jaen, Spain) and Paul van Roye (Darmstadt, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells ex...