US Patent Issued to California Institute of Technology on Aug. 12 for "Engineered synthase for production of tryptophan derivatives and intransigent substrates" (American, Swiss, Spanish Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,029, issued on Aug. 12, was assigned to California Institute of Technology (Pasadena, Calif.).

"Engineered synthase for production of tryptophan derivatives and intransigent substrates" was invented by David K. Romney (Pasadena, Calif.), Javier Murciano Calles (Ubeda Jaen, Spain) and Jori E. Wehrmuller (Hohenrain, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids."

The patent was filed on De...