US Patent Issued to California Institute of Technology, The Rockefeller University on Nov. 4 for "Anti-HIV vaccine antibodies with reduced polyreactivity" (California, New York Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,990, issued on Nov. 4, was assigned to California Institute of Technology (Pasadena, Calif.) and The Rockefeller University (New York).

"Anti-HIV vaccine antibodies with reduced polyreactivity" was invented by Stuart A. Sievers (Encino, Calif.), Jennifer Keeffe (Pasadena, Calif.), Michel C. Nussenzweig (New York) and Pamela J. Bjorkman (La Canada, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides novel broadly neutralizing anti-HIV antibodies and antigen-binding fragments thereof. The disclosed anti-HIV antibodies exhibited improved biophysical properties, e.g., reduced polyreactivity, prolonged half-life, while retaining...