US Patent Issued to Brown University, SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE on Nov. 11 for "Compositions and methods for the modulation of the corticotropin releasing factor binding protein and the treatment of alcohol use disorder" (California, Rhode Island Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,594, issued on Nov. 11, was assigned to Brown University (Providence, R.I.) and SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (San Diego).

"Compositions and methods for the modulation of the corticotropin releasing factor binding protein and the treatment of alcohol use disorder" was invented by Carolina L. Haass-Koffler (Providence, R.I.), Douglas James Sheffler (San Diego) and Nicholas David Peter Cosford (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Stress responses involve corticotropin releasing factor (CRF), the two cognate receptors (CRF1 and CRF2) and the CRF-binding protein (CRFBP). Utilizing a novel cell-based assay, a C-t...