US Patent Issued to Bristol Myers-Squibb on Nov. 18 for "Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,290, issued on Nov. 18, was assigned to Bristol Myers-Squibb Co. (Princeton, N.J.).

"Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses" was invented by David R. Tortolani (Skillman, N.J.), Zheming Ruan (Dayton, N.J.), Michael G. Yang (Narberth, Pa.) and Zili Xiao (East Windsor, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds having the following formula I: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein all substituents are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNAlpha by acting on Tyk-2 to cause signal transduction inhibition."

The pa...