US Patent Issued to Bristol-Myers Squibb on Dec. 9 for "1H-benzo[Dimidazole derivatives as TLR9 inhibitors for the treatment of fibrosis" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,188, issued on Dec. 9, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).

"1H-benzo[Dimidazole derivatives as TLR9 inhibitors for the treatment of fibrosis" was invented by David S. Yoon (Ambler, Pa.), Alicia Regueiro-Ren (New Hope, Pa.), Michael Mandler (Lawrenceville, N.J.), Shoshana L. Posy (Highland Park, N.J.) and Chunjian Liu (Pennington, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to 1H-benzo[d]imidazole derivatives of formula (I) or a salt thereof. The present compounds are inhibitors of TLR9 and useful in treating preventing, or slowing fibrotic diseases, such as e.g. liver fibrosis, renal fibro...