ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,428, issued on April 29, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).

"Tricyclic heteroaryl compounds useful as IRAK4 inhibitors" was invented by Satheesh Kesavan Nair (Bangalore, India), Venkatram Reddy Paidi (Bangalore, India), Kandhasamy Sarkunam (Hosur, India), Ramesh Kumar Sistla (Bangalore, India), John Hynes (Washington Crossing, Pa.) and Natesan Murugesan (Princeton Junction, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds of Formula (I) or a salt or prodrug thereof, wherein: X1 and X2 are independently C or N, provided that zero or one of X1 and X2 is N; Ring A represented by the structure is: or; a...