US Patent Issued to Boehringer Ingelheim International on Sept. 23 for "Spiro[3H-indole-3,2'-pyrrolidin-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors" (Austrian, German Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. RE50,594, issued on Sept. 23, was assigned to Boehringer Ingelheim International GmbH (Ingelheim Am Rhein, Germany).

"Spiro[3H-indole-3,2'-pyrrolidin-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors" was invented by Andreas Gollner (Vienna), Joachim Broeker (Moedling, Austria), Nina Kerres (Vienna), Christiane Kofink (Perchtoldsdorf, Austria), Juergen Ramharter (Vienna), Harald Weinstabl (Vienna), Annika Gille (Ulm, Germany), Stefan Goepper (Biberach an der Riss, Germany), Manuel Henry (Schemmerhofen, Germany) and Guenther Huchler (Hochdorf, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention encompasses intermediates fo...