ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,278, issued on Aug. 5, was assigned to Board of Trustees of Michigan State University (East Lansing, Mich.).
"Mimetics of heparin oligosaccharides" was invented by Xuefei Huang (Okemos, Mich.) and Jicheng Zhang (East Lansing, Mich.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to disaccharides with defined sulfation patterns, and oligosaccharide mimetics comprising the disaccharides as repeating units linked in a head to tail fashion. The present disclosure further relates to methods of making the same, and to methods of using the same to mediate cell proliferation, cell differentiation, amyloid plaque formation, anti-...