ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,447, issued on May 13, was assigned to BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA and OHIO STATE INNOVATION FOUNDATION.

"Gene therapy for juvenile Batten disease" was invented by Tammy Kielian (La Vista, Neb.) and Kevin Foust (New Albany, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for the treatment of Juvenile Neuronal Ceroid Lipofuscinosis (JNCL), also known as Juvenile Batten Disease, are provided herein. In certain embodiments the compositions include but are not limited to adeno-associated viral (AAV) constructs, including self-complementary adeno-associated viral (sc-AAV) constructs, that express the human ...