ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,598, issued on Nov. 18, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).
"Identification of epigenetic alterations in DNA isolated from exosomes" was invented by Raghu Kalluri (Houston).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods of diagnosing and prognosing disease by analyzing the methylation status of exosomal DNA. In particular, exosomal DNA, in particular exosomal DNA isolated from exosomes that originated from a diseased cell, is analyzed for either a global methylation fingerprint or for a particular methylation status at one or more genomic loci, thereby providing info...