US Patent Issued to Board of Regents, The University of Texas System on June 24 for "Glutaminase inhibitor therapy" (Texas Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,336,976, issued on June 24, was assigned to Board of Regents, The University of Texas System (Austin, Texas).

"Glutaminase inhibitor therapy" was invented by Timothy Heffernan (Sugar Land, Texas), Jeffrey Kovacs (Pearland, Texas), Nakia Spencer (Houston) and Christopher Bristow (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production...