US Patent Issued to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM on Dec. 9 for "Small molecule PARG inhibitors and methods of use thereof" (Texas, Arkansas, Missouri Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,188, issued on Dec. 9, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).

"Small molecule PARG inhibitors and methods of use thereof" was invented by John A. Tainer (Houston), Zamal Ahmed (Houston), Darin E. Jones (Little Rock, Ark.), In-Kwon Kim (St. Louis), Tom Ellenberger (St. Louis) and Chris Ho (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of inhibiting PARG in cancer cells, including methods comprising administering a PARG inhibitor that modulates position Tyr795 in PARG. Also provided herein are methods of treating and/or preventing cancer comprising administeri...