US Patent Issued to Board of Regents, The Univeristy of Texas System on Oct. 14 for "Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists" (Texas Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,686, issued on Oct. 14, was assigned to Board of Regents, The Univeristy of Texas System (Ausitn, Texas).

"Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists" was invented by Jia Zhou (Galveston, Texas), John A. Allen (Galveston, Texas), Pingyuan Wang (Galveston, Texas) and Daniel E. Felsing (Galveston, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments are directed to novel GPR52 activators. In particular, a series of novel 1-(pyrimidin-4-yl)indoline-4-carboxamide analogs that have been identified as potent and selective GPR52 agonists. The optimized GPR52 agonist that, for example, can be used as a valuable pharmacological t...