ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,432, issued on Dec. 9, was assigned to Biotheranostics Inc. (San Diego) and The General Hospital Corp. (Boston).

"Tumor grading and cancer prognosis" was invented by Mark G. Erlander (Carlsbad, Calif.), Xiao-Jun Ma (San Diego) and Dennis Sgroi (Winchester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to cancer. In particular, the disclosure includes the identities of genes that are expressed in correlation with tumor grade. The levels of gene expression are disclosed as a molecular index for determining tumor grade in a patient...