ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,427,173, issued on Sept. 30, was assigned to Biomed Valley Discoveries Inc. (Kansas City, Mo.).

"Use of bacteria, bacterial products, and other immunoregulatory entities in combination with anti-CTLA-4 and/or anti-PD-1 antibodies to treat solid tumor malignancies" was invented by Shibin Zhou (Owings Mills, Md.), Bert Vogelstein (Baltimore), Kenneth Kinzler (Baltimore), Kibem Kim (Lutherville, Md.) and Saurabh Saha (Wellesley Hills, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently disclosed subject matter provides methods and kits for treating solid tumors in a subject by using a combination of anti-CTLA-4 and/or anti-PD-1 antibodies w...